儿童肥胖与维生素D关系的研究进展

Research progress on the relationship between childhood obesity and vitamin D

关键词:  儿童  肥胖  维生素D

Key words:  children  obesity  vitamin D

摘要:

近年来儿童肥胖与维生素D的关系成为研究热点。肥胖儿童体内维生素D水平减低，可能与肥胖者活动减少、接受日晒时间少，皮肤合成维生素D减少、大量维生素D存储于脂肪中导致其生物利用率减低及肝脏维生素D的25-羟化减少有关。减少体脂水平可能有助于恢复正常的维生素D水平。大部分研究结果支持维生素D缺乏状态可能是导致儿童肥胖发生、发展的重要原因之一，然而具体作用机制不明。补充维生素D是否可降低体脂含量从而改善肥胖患儿的预后仍不十分明确。本文就儿童肥胖与维生素D缺乏的关系及其相互影响的可能机制进行综述。

Abstract:

In recent years, the relationship between children obesity and vitamin D has become a research hotspot. Decreased vitamin D levels in obese children may be associated with reduced activity, less exposure to sunlight, reduced skin synthetic vitamin D, reduced bioavailability of vitamin D stored in fat and reduced 25-hydroxylation of vitamin D in liver. Reducing body fat levels may help restore normal vitamin D levels. While the effect of vitamin D deficiency on children obesity is supported by most of the research results and vitamin D deficiency may be one of the important reasons for the occurrence and development of children obesity, the specific mechanism is unclear. Therefore, the relationship between children obesity and vitamin D deficiency needs to be further studied.