| 摘要: |
| 多酚是天然抗氧化剂，具有两个重要的生理效应，清除自由基和影响酶的表达。2型糖尿病的发病主要与胰岛素抵抗、胰岛素分泌异常有关。氧化应激可影响胰岛素的敏感性或直接影响β-细胞数量，与糖尿病的发生有关。多酚可以通过抗氧化及调节糖代谢酶的活性等方面预防糖尿病的发生。本文对多酚抗糖尿病作用的研究进展作一综述。 |
| 关键词: 糖尿病 氧化应激 多酚 |
| DOI：10.11724/jdmu.2016.06.21 |
| 分类号:R151 |
| 基金项目:基金项目：辽宁省教育厅科学技术研究项目（L2015148） |
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| Research progress on antidiabetic effects of polyphenols |
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SHI Lin-lin1, LIU Xiao-fang2
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1.Department of Nutrition, Tianjin Third Hospital, Tianjin 300017, China;2.Department of Nutrition and Food Hygiene, College of Public Health, Dalian Medical University, Dalian 116044, China
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| Abstract: |
| Polyphenols are natural antioxidants, have two important physiological effects, scavenging free radicals and affecting the expression of enzymes. The incidence of diabetes is mainly related to insulin resistance and insulin secretion. Oxidative stress can affect the sensitivity of insulin or directly affect the amount of pancreatic β-cells, which is related to the occurrence of diabetes. Polyphenols can prevent the occurrence of diabetes by antioxidant and regulating the activity of glucose metabolism enzymes. Here, we review the progress of the effect of polyphenols on diabetes. |
| Key words: diabetes oxidative stress polyphenol |
