卵巢内生殖干细胞的研究进展和应用

Research progress and application of ovarian germ stem cells

关键词:  生殖干细胞  卵母干细胞  卵巢表面上皮

Key words:  germline stem cells  oogonial stem cells  ovarian surface epithelium

摘要:

对于哺乳动物卵巢中生殖干细胞(germline stem cells，GSCs)是否存在一直有争议，以往的研究表明哺乳动物卵巢中卵泡是不可再更新的，但最近基于小鼠的研究对其提出了异议，并通过大量实验来证实。最新的研究更从人类的卵巢中分离出生殖干细胞，这一发现对生殖干细胞进一步的研究和未来的临床应用提供了动力。因此本文对生殖干细胞的研究进展及应用做一综述。

Abstract:

[Abstract] It's always controversial whether ovarian germ stem cell (GSCs)exist in mammals. Previous studies show that mammals in ovarian follicle is not to update, but recent research on its put forward the objection through a lot of experiments.The latest research have isolated GCSs from human ovarian, the discovery of GSCs provide motivation to further research and clinical application in future. So in this article, the research progress and application of GSCs in the future are reviewed.