| 摘要: |
| 压力性尿失禁（stress urinary incontinence，SUI）在女性中发病率很高。目前，没有长期有效并且伤害很低的治疗方法。而干细胞以其诸多不可替代的优点渐渐被人们所认知，并应用到压力性尿失禁的治疗当中。干细胞有自我更新以及向不同类型细胞分化的能力。体内研究证明，将干细胞移植到压力性尿失禁患者尿道横纹括约肌上可以促进括约肌的再生。移植的细胞还可以释放增长因子促进神经和肌肉的再生。本文对干细胞治疗SUI的发展进程进行综述。 |
| 关键词: 干细胞 尿失禁 尿道横纹括约肌 |
| DOI：10.11724/jdmu.2011.04.21 |
| 分类号:R711.4 |
| 基金项目: |
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| Stem cell for the treatment of stress urinary incontinence |
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Xü Lei, SHI Hong
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Department of Gynaecology and Obstertrics, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
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| Abstract: |
| Stress urinary incontinence (SUI) is highly prevalent in females.As of now, the long-term and low invasive treatment is still not available. Adult stem cells have many irreplaceable advantages and the ability to self-renew and to differentiate into other cell types. In the past few years, in vivo studies have described the use of stem cells transplanted into the site of the rhabdosphincter in patients with stress urinary incontinence that may produce sphincter regeneration. Transplanted cells may also release factors to promote nerve and muscle regeneration. We review the use of stem cell therapy for SUI. |
| Key words: stem cell urinary incontinence rhabdosphincter |
