| 摘要: |
| ［目的］ 观察比较3%盐酸氯普鲁卡因（可普诺）在硬膜外麻醉中分次给药和微量泵持续给药效果的区别。［方法］ 选择单纯硬膜外麻醉患者100例，随机分成两组，记录麻醉起效后病人的平均动脉压、阻滞范围变化和心率变化，以及肌松欠佳和镇痛欠佳的例数。［结果］ 微量泵持续给药方式与分次给药方式相比对病人的影响更小，麻醉效果更佳，差异有显著性意义：微量泵持续输注3%盐酸氯普鲁卡因组（微量泵组）的最大阻滞范围明显小于对照组，差异有显著性意义（P<0.01）；术中平均动脉压下降幅度与对照组相比明显减少，差异有显著性意义（P<0.01）；麻醉以后微量泵组）心率增加明显小于对照组，差异有显著性意义（P<0.01），肌松效果欠佳和辅助镇痛例数（微量泵组）组明显少于对照组（P<0.01）。［结论］ 应用微量泵持续性给药能够取得完善的麻醉效果，对病人干扰更小，更安全。 |
| 关键词: 微量泵 3%盐酸氯普鲁卡因 硬膜外麻醉 |
| DOI：10.11724/jdmu.2010.01.16 |
| 分类号:R614.4 |
| 基金项目: |
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| Clinical value of 3% chlorprocaine hydrochloride for epidural anesthesia with micro-pump |
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WANG Lei1, YUAN Li-gang2, ZHAO Fu-long1
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1.Department of Anesthesiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China;2.Department of Anesthesiology, the Second Hospital of Liaohe Oil Field, Panjin 124012, China
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| Abstract: |
| ［Objective］ To compare the efficacies of intermittent infusion and continuous infusion of 3% chlorprocaine hydrochloride with micro-pump in epidural anesthesia. ［Methods］ One hundred patients were randomly divided into two groups, the maximum block range, MAP, HR, The number of cases of muscle relaxant effects of poor and supporting analgesia were recorded. ［Results］ The effect of continuous infusion with micro-pump was better than intermittent infusion and significant differences in analgesia effects were observed. The maximum block range of micro-pump group was significantly less than that of the control group (P<0.01). The MAP of micro-pump group decreased during the anesthesia was significantly less than that in the control group (P<0.01). The heart rate increased was significantly less than that in the control group (P<0.01). The number of cases of muscle relaxant effects of poor and supporting analgesia was significantly less than that in the control group (P<0.01). ［Conclusion］ Continuous infusion of 3% chlorprocaine hydrochloride with micro-infusion pump in epidural anesthesia is perfect and safe. |
| Key words: micro-pump 3% chlorprocaine hydrochloride epidural anesthesia |
