| 摘要: |
| 本文综合近年来国内外有关多环芳烃（PAHs）致癌性的研究资料，着重从细胞色素P450、环氧化物水解酶、谷胱甘肽硫转移酶、PAH-DNA加合物等方面，概述了多环芳烃的致癌性及其机制，为PAHs的致癌机制研究提供一定的思路。 |
| 关键词: 多环芳烃 致癌性 机制 |
| DOI：10.11724/jdmu.2009.05.27 |
| 分类号:R994.6 |
| 基金项目: |
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| Carcinogenicity of polycyclic aromatic hydrocarbons and research progress of the mechanisms |
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JIA Hong-ning, DAI Hong
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Department of Occupational and Environmental Health, Dalian Medical University, Dalian 116044, China
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| Abstract: |
| This paper reviews investigations about the carcinogenicity of polycyclic aromatic hydrocarbons (PAHs) and mainly expounds cytochrome P450, epoxide hydrolase, glutathione S-transferase, PAH-DNA adducts in an attempt to provide ideas for a deep research in the carcinogenic mechanisms of PAHs. |
| Key words: polycyclic aromatic hydrocarbon (PAHs) genotoxicity mechanism |
