| 摘要: |
| ［目的 ］探讨心肌型脂肪酸结合蛋白（H-FABP）与D-D聚体在急性心肌梗死早期中的诊断价值。［方法］ 采用酶联免疫分析法、酶免疫法测定42例心肌梗死患者，31例不稳定性心绞痛患者，25例稳定性心绞痛患者及30例健康体检者H-FABP、D-D聚体。［结果］ 急性心肌梗死组（AMI）的H-FABP、D-D聚体水平明显高于稳定性心绞痛组（SA），P<0.01；不稳定性心绞痛组的（UA）H-FABP、D-D聚体水平高于稳定性心绞痛组（SA），P<0.05，稳定性心绞痛组的（SA）H-FABP、D-D聚体水平与正常对照组相比差异无显著性意义（P>0.05）。［结论］ H-FABP用于AMI的早期诊断具备可行性，而D-D聚体可以作为AMI诊断的参考指标，两者联合检测有助于提高AMI的早期诊断。 |
| 关键词: 心肌型脂肪酸结合蛋白H-FABP D-D聚体 急性心肌梗死 |
| DOI：10.11724/jdmu.2009.05.22 |
| 分类号:R466.1 |
| 基金项目: |
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| Combined detection of H-FABP and D-D’s value in acute myocardial infarction |
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WANG Wei-dong1, MA Rong1, LI Xiao-lan1, DONG Min2
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1.Department of Clinical Laboratory, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China;2.Department of Clinical Laboratory,Xinhua Hospital of Dalian University, Dalian 116020, China
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| Abstract: |
| ［Objective］ To study the combined detection of serum H-FABP and D-D diagnosis value in acute myocardial infarction. ［Methods］ Immunological analysis methods, enzyme immunology methods and latex strengthing immunological turbidimetry were used to detect H-FABP and D-D in 42 patients with myocardial infarction, 31 cases with unsolid cardiac angina, 25 cases with solid cardiac angina and 30 healthy controls. ［Results］ H-FABP and D-D's levels of AMI were remarkably higher than those in SA (P<0.01). H-FABP and D-D's levels of UA was higher than those in SA (P<0.05). H-FABP and D-D's levels of SA and control group had no remarkable distinction (P>0.05). ［Conclusion］ H-FABP has feasibility in early diagnose of AMI, but D-D can be considered as consult index of AMI diagnose. So the combined detection of them may contribute to the early diagnose of AMI. |
| Key words: H-FABP D-D acute myocardial infarction (AMI) |
