引用本文:江芳,张卓然,金宁.当归补血饮、莪术对体外H22、K562、Yac-1细胞作用的研究[J].大连医科大学学报,2000,22(1):.
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当归补血饮、莪术对体外H22、K562、Yac-1细胞作用的研究
江芳1, 张卓然1, 金宁2
1.大连医科大学微生物教研室,116027;2.大连医科大学检验系94级
摘要:
应用MTT比色分析法观察当归补血饮及莪术两味中药在体外对H22、K562、Yac-1三种肿瘤细胞的影响.结果表明:100mg/ml的当归补血饮对三种肿瘤细胞的抑制率分别为:30.3%、43.4%、36.7%;莪术的抑制率分别为:33.2%、42.7%、37.0%,与作为阳性对照的环磷酰胺相比无明显差异(P>0.05),二者合用,抑制效果更为明显.结论:两种中药均有明显而肯定的抗肿瘤作用.
关键词:  当归补血饮  莪术  体外抗肿瘤
DOI:10.11724/jdmu.2000.01.20
分类号:R282.705
基金项目:
Studies of Dangguibuxue Decoction and Ezhu on the H22,K562 and Yac-1 tumor cells in vitro
Jiang Fang,Zhang Zhuoran,Jin Ning
Department of Microbiology,Dalian Medical University,Dalian,China
Abstract:
The malignant tumor endangered human health seriously. The effects of Dangguibuxue Decoction(DD) and Ezhu on the H22,K562 and Yac-1 tumor cells in vitro were observed with the MTT assay in order to develop antitumor traditional Chinese medicine.Result:the inhibiting rate of DD to tumor cells were 30.3%, 43.4% and 36.7% but Ezhu were 33.2%, 42.7% and 37.0%. The difference wasn't statistically significant(P>0.05)contrasted with CYS as positive control. The DD and Ezhu had better inhibiting effects.Conclusion: The DD and Ezhu had antitumor effects obviously
Key words:  DD  Ezhu  antitumor in vitro