引用本文:马悦,马洪刚.血清中输血传播病毒检测及临床意义的探讨[J].大连医科大学学报,2000,22(1):.
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血清中输血传播病毒检测及临床意义的探讨
马悦1, 马洪刚2
1.大连医科大学第二临床学院检验科,116027;2.大连医科大学检验系94级
摘要:
目的:研究血清中输血传播病毒(TTV)抗体的检测及其临床意义.方法:采用间接ELISA法检测108例(包括20例献血员)血清中输血传播病毒(TTV)抗体.结果:分析88例患者,其中11例血透患者、35例乙肝患者、26例丙肝患者、4例庚肝患者、12例非甲~庚型肝炎患者及20例正常献血员,TTV抗体阳性率分别为27.3%、20.0%、7.8%、0%、25.0%与5.0%.结论:在正常人群中TTV健康携带者较常见;血液透析患者与非甲~庚型肝炎患者是TTV感染的高危人群;乙型及丙型肝炎常重叠TTV感染.
关键词:  输血传播病毒(TTV)  肝炎  酶联免疫
DOI:10.11724/jdmu.2000.01.21
分类号:R373
基金项目:
Detection of transfusion transmitted virus antibody in serum and investigation clinical significance
Ma Yue,Ma Honggang
Department of clinical laboratory,the Second Affiliated Hospital,Dalian Medical University, Dalian, China
Abstract:
objective To investigate the detection of transfusion transmitted virus(TTV) antibody in serum and the clinical significance.Method 108 serum samples(including 20 blood donors) were detected for transfusion transmitted virus(TTV) antibody by indirect ELISA analysis. Result 88 samples including 11 hemodialysis patients,35 patients with hepatitis B,26 patients with hepatitis C,4 patients with hepatitis G,12 patients with non A-G hepatitis and 20 blood donors,the positiverates of TTV antibody were 27.3%, 20.0%,7.8%,0%,25.0% and 5.0%. Conclusion TTV infection is common in the normal population; Patients with non A-G hepatitis and hemodislysis patients are at high risk for TTV infection;Hepatitis B and C are usually companied with TTV infection.
Key words:  transfusion transmitted virus(TTV)  hepatitis  ELISA