摘要: |
寨卡(ZIKA)病毒感染相关神经系统并发症为目前的研究热点,尤其是与之相关的吉兰-巴雷综合征和小头畸形。诊断寨卡病毒感染主要通过逆转录-聚合酶链反应,影像学检查可提高合并神经系统并发症诊断的准确率。然而,目前尚无针对寨卡病毒感染的特效药物及疫苗。因寨卡病毒感染与神经系统疾病密切相关,本文就寨卡病毒的流行特征、神经系统并发症、诊断及治疗等方面进行综述。 |
关键词: 寨卡病毒 吉兰-巴雷综合征 小头畸形 诊断 并发症 |
DOI:10.11724/jdmu.2018.06.17 |
分类号:R737. 33 |
基金项目:基金项目:国家自然科学基金项目(81471215, 81271211);江苏省社会发展重点病种规范化诊疗项目(BE2015665);江苏省自然科学基金项目(BK20151592);江苏省333高层次人才项目(2016-III-0950) |
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Progress in the study of the neurological complications related to ZIKA virus infection |
LIANG Yan1, XU Jun2
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1.Department of Neuyology, Subei People's Hospital,Yangzhou 225001,China;2.Department of Neurology, Beijing TianTan Hospital, Beijing 100050,China
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Abstract: |
The neurological complications associated with ZIKA virus infection are currently the focus of research, especially the related Guillain-Barré syndrome and microcephaly. Diagnosis of ZIKA virus infection is mainly by virus detection with reverse transcription-polymerase chain reaction. Imaging examination can improve the accuracy of the diagnosis of complications of the nervous system. However, there are currently no specific drugs and vaccines for ZIKA virus infection. Because ZIKA virus infection is closely related to nervous system diseases, we reviewed the epidemic characteristics of ZIKA virus, neurological complications, diagnosis and treatment. |
Key words: ZIKA virus Guillain-Barré syndrome microcephaly diagnosis complication |