眼动脱敏与再加工联合艾司西酞普兰对抑郁症的疗效

Efficacy analysis of combination of eye movement desensitization and reprocessing（EMDR）with escitalopram for depressed patients

关键词:  EMDR  艾司西酞普兰  应激性生活事件  抑郁症

Key words:  EMDR  escitalopram  stressful life event  depressive disorder

摘要:

目的　探讨眼动脱敏与再加工(eye movement desensitization and reprocessing, EMDR)联合艾司西酞普兰(Escitalopram citalopram, Es)对应激性生活事件的抑郁症患者的疗效。　方法　将90例患者随机分成Es+EMDR、Es和EMDR治疗组。在治疗前及治疗后的2、4、6周采用汉密尔顿抑郁量表（hamilton depression scale-17 item，HAMD-17）评分进行疗效评定。　结果　治疗后三组评分与治疗前比较，差异均有显著性意义（P<0.05）。治疗后第2、4周末Es+EMDR治疗组评分明显低于Es及EMDR治疗组（P<0.05）。6周末Es+EMDR治疗组评分仍低于EMDR治疗组（P<0.05），但与Es治疗组比较，差异无显著性意义（P>0.05）。　结论　相比Es及EMDR治疗，Es+EMDR治疗起效更快，疗效更稳定，可以有效提高抑郁症患者临床痊愈率。

Abstract:

Objective　 To explore the combination therapeutic effect of eye movement desensitization and reprocessing (EMDR) and escitalopram citalopram for depression patients with a stressful life event.　Methods　 A total of 90 patients were selected and were randomly divided into Es+EMDR treatment group, Es treatment group, and EMDR treatment group. Hamilton Depression Scale (HAMD) was adopted to evaluate the efficacy.　Results　 At the 2nd and 4th weekend, the HAMD scores were significantly lower after treatment in all three groups. But the score of Es+EMDR was lower than the other groups（P<0.05）. And at the 6th weekend, the effect in the Es+EMDR treatment group was more preferable compared to the EMDR treatment group (P<0.05), but not preferable in the escitalopram citalopram treatment group (P>0.05).　Conclusion　 The combination of escitalopram citalopram+EMDR treatment had more advantages in fast working time and stable therapeutic effect. It could effectively improve the clinical cure rate of depression.