高血压合并冠心病患者动态血压变异性的临床研究

Clinical research of ambulatory blood pressure variability in patients with hypertension and coronary heart disease

关键词:  24 h动态血压  高血压  冠心病

Key words:  [Key words]　24 h ambulatory blood pressure  hypertension  coronary heart disease (CHD)

摘要:

[摘要]　目的　探讨高血压合并冠心病与否对动态血压的影响及动态血压监测的重要性。 　方法　收集原发性高血压患者152例。按冠状动脉造影或冠脉螺旋CT(VCT)结果分为冠心病组64例和非冠心病组88例，行24 h动态血压监测，对相关数据统计分析。　结果　冠心病组24 h平均收缩压及舒张压、昼间平均收缩压及舒张压和夜间平均收缩及舒张压明显高于非冠心病组（P<0.05）；夜间收缩压和舒张压下降率明显小于非冠心病组（P<0.05）；冠心病组收缩压和舒张压勺型比例小于非冠心病组（P<0.05）；晨峰出现频率大于非冠心病组(P<0.05)，差异有显著性意义。　结论　24 h动态血压监测可较客观准确的测出高血压患者昼夜血压变化情况，高血压合并冠心病患者较未合并者的血压波动性更大。动态血压的监测对高血压并发冠心病的患者在预防、诊断及治疗效果评估方面有很重要的意义。

Abstract:

[Abstract] Objective　To discuss the influence of hypertension with or without coronary heart disease (CHD) to ambulatory blood pressure, as well as the significance of ambulatory blood pressure monitoring. 〖WTHZ〗Methods　We collected 152 cases of primary hypertension. The patients were divided into 2 groups by the results of coronary angiography or spiral CT coronary artery (VCT): CHD group of 64 cases and non CHD group (control group) of 88 cases. They received 24 h ambulatory blood pressure monitoring. The data were compared by statistical analysis. 〖WTHZ〗Results　The 24 h average systolic and diastolic blood pressures and the average diastolic and systolic blood pressures at day and night were significantly higher in the CHD group than those in the control group (P<0.05). The rate of decline in diastolic and systolic blood pressures at night was obviously less in the CHD group than those in the control group. Scoop type proportional of diastolic and systolic blood pressure was less in the CHD group than those in the control group (P<0.05). The frequency of occurrence of morning peak was more than the control group (P<0.05), and the differences were statistically significant. 〖WTHZ〗Conclusion〖WTBZ〗 24 h ambulatory blood pressure monitoring can objectively and accurately measure the changes of the day and night blood pressure in hypertension patients and the volatility is larger in patients of hypertension with CHD than in those without CHD. Ambulatory blood pressure monitoring has a significant value to the patients of hypertension with CHD in prevention, diagnosis and assessment of therapeutic effect.