摘要: |
侵袭性垂体腺瘤的诊断缺乏特异性的分子标记物,主要依靠影像学,术中所见和术后病理学检查。侵袭性垂体腺瘤的治疗包括手术治疗、药物治疗和放疗。影像学、神经内镜、术中导航的应用和发展、药物治疗和放射治疗水平的提高显著改善了侵袭性垂体腺瘤的治疗效果。侵袭性垂体腺瘤的治疗还需要多学科干预和密切的随访。 |
关键词: 侵袭性垂体腺瘤 诊断 治疗 |
DOI:10.11724/jdmu.2014.01.23 |
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Diagnosis and treatment of invasive pituitary adenoma |
WEI Zhen-qing 1,2,WANG Ren-zhi 1,YAO Yong 1,DENG Kan 1, WANG Jian-xin 1, LIU Xiao-hai 1,DAI Cong-xin 11,2
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1.Department of Neurosurgery,Chinese Academy of Medical Sciences,Peking Union Medical College Hospital,Beijing 100730, China;2. Department of Neurosurgery, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
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Abstract: |
[Abstract] Diagnosis of invasive pituitary adenoma(IPA)depends mostly on imaging, intra-operative findings and postoperative pathological examination and is short of molecular biomarkers. Treatment of IPA consists of surgery, chemotherapy and radiation therapy. The application and development of imaging, endoscopy, intraoperative navigation and the improvement of chemotherapy and radiation therapy significantly improved the treatment effect of invasive pituitary adenomas. However, IPA still needs multidisciplinary intervention and close follow-up. |
Key words: [Key words] invasive pituitary adenoma diagnosis treatment |