血浆B型钠尿肽与急性心肌梗死预后关系的研究进展

Advances in research of plasma B-type natriuretic peptide in indicating prognosis of acute myocardial infraction

关键词:  B型钠尿肽  急性心肌梗死  预后

Key words:  B-type natriuretic peptide(BNP)  acute myocardial infarction (AMI)  prognosis

摘要:

B型钠尿肽（B-type natriuretic peptide，BNP）是一种主要由心室肌细胞分泌的肽类心脏神经激素，在循环系统的体液调节中发挥着重要作用。大量研究表明，急性心肌梗死(acute myocardial infarction, AMI)患者的血浆BNP水平常升高，且其升高程度与患者心脏功能有关，可能也与患者预后存在某些关联。本文仅就血浆BNP对急性心肌梗死患者预后意义的相关研究进展作一简要介绍。

Abstract:

B-type natriuretic peptide(BNP), a cardiac neural peptide hormone secreted chiefly by ventricular myocardia, plays an important role in homeostasis of circulatory system. Lots of experimental evidences revealed that the plasma concentration of BNP was raised in the cases of acute myocardial infarction (AMI), and the level of BNP's concentration might be related to the prognosis of patient with AMI. The present review would give a simple presentation of current status on relationship between BNP and the AMI prognosis.