97例乳腺癌保乳治疗的临床疗效观察

Clinical outcome and cosmetics in breast cancer patients treated with conservative surgery and radiotherapy

关键词:  乳腺癌  放射治疗  保乳手术  美容效果

Key words:  early breast cancer  radiotherapy  conservative surgery  cosmetic result

摘要:

[目的] 观察乳腺癌保乳手术加放疗的临床疗效及美容效果。〖ＨＴH〗[方法] 97例乳腺癌行保乳手术后接受术后放疗，用6MV-X射线照射全乳房，采用乳房切线野照射，每次2 Gy，每周照射5次，至DT 50Gy/25f/35d。瘤床区加量采用9~12 MeV电子线，每次2 Gy,共5次，DT 10 Gy。有腋窝淋巴结转移，给以同时行锁骨上区预防性照射DT 50Gy/25f/35d。〖ＨＴH〗[结果] 中位随访时间为60个月（30～72个月），总生存率为97.3%，局部复发率为3.21%，无病生存率为94.7%。乳房美容效果好，优良率达93.8%。〖ＨＴH〗[结论] 乳腺癌保乳手术加放疗可以获得满意的控制率和美容效果。

Abstract:

[Objective] To evaluate the effectiveness and the cosmetic result of radiotherapy after breast conserving surgery for early breast cancer. [Methods] A total of 97 early invasive breast carcinoma in women who had undergone previous breast-conserving surgery were treated with postoperative irradiation. [Results] The median follow-up time was 60 months,the overall survival rate was 97.3% and the locoregional recurrence rate was 3.21%,as calculated using the Kaplan-Meier method. Excellent and good cosmetic result was noted in 91 patients. [Conclusion] Breast-conserving therapy,consisting of breast-conserving surgery followed by breast radiotherapy, has therefore become the standard regimen for treatment of early invasive breast cancer.