| 摘要: |
| 微小RNA(miRNAs)作为一类内源性非编码小分子RNA，是高等生物生长发育的重要调节因子。miR-21被认定为miRNA转录的主要驱动力，其在人类多种实体肿瘤中高表达，参与细胞增殖、分化、凋亡，且与肿瘤生长、侵袭、转移等密切相关。 |
| 关键词: miR-21 实体肿瘤 进展 |
| DOI：10.11724/jdmu.2012.02.20 |
| 分类号: |
| 基金项目: |
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| Development of research on the relationship between miRNA-21 and solid tumors |
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LI Xian-cheng，LI Xiu-nan，SONG Xi-shuang
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Department of Urology, the First Affiliated Hospital of Dalian Medical University，Dalian116011, China
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| Abstract: |
| miRNAs are endogenous, non-coding small RNAs that play an important role in the growth and development of higher organisms. miR-21 is recognized as the main driving force of miRNA's transcription, which has a high-expression in many solid tumors of human and take part in cell proliferation, differentiation and apoptosis, and so that it is closely related to tumors' growth, invasion and metastasis. |
| Key words: miRNA-21 solid tumors development |
