甲状腺癌构成比变化分析

Analyze change of constituent ratio of thyroid carcinoma

关键词:  甲状腺癌  构成比  结节性甲状腺肿  桥本甲状腺炎  微小癌

Key words:  thyroid neoplasms  constituent ratio  nodular goiter  hashimoto disease  microcarcinoma

摘要:

［目的］探讨近年来甲状腺癌的构成比变化。［方法］回顾性分析2002年1月~2009年12月初次于大连医科大学附属第一医院行甲状腺手术的6336例病理资料，构成比行卡方或卡方趋势分析检验。［结果］甲状腺癌共1151例（ 乳头状癌占95.57%），其占甲状腺手术病例的构成比由2002年的11.24%逐渐上升至2009年的21.22% （P<0.01）。2008年和2009年的甲状腺微小癌、合并结节性甲状腺肿甲状腺癌及合并桥本甲状腺炎甲状腺癌的构成比与2005年相比，差异有显著性意义（P均<0.05）。［结论］2002~2009年甲状腺手术患者中甲状腺癌的构成比呈逐渐上升趋势，且以乳头状癌为主。近两年来微小癌、合并结节性甲状腺肿甲状腺癌及合并桥本甲状腺炎甲状腺癌的构成比均较前明显增高。

Abstract:

［Objective］To investigate the change of the constituent ratio of thyroid carcinoma from 2002 to 2009.［Methods］Analyzed the pathologic data of 6336 patients who suffered first thyroidectomy in the first affiliated hospital of Dalian medical university from January 2002 to December 2009 retrospectively,and checked the change of the constituent ratio with chi square or chi square for trend analysis.［Results］There were 1151 patients of thyroid carcinoma (papillary thyroid carcinoma accounted for 95.57%),and the constituent ratio of thyroid carcinoma among the patients of thyroidectomy increased gradually from 11.24% in 2002 to 21.22% in 2009 (P<0.01).Compared with 2005,the constituent ratio of thyroid microcarcinoma,carcinoma with nodular goiter ,and carcinoma with Hashimoto thyroiditis all greatly increased in 2008 and 2009 (P<0.05).［Conclusions］The constituent ratio of thyroid carcinoma increased gradually from 2002 to 2009,most of the thyroid carcinoma are papillary.The constituent ratio of thyroid microcarcinoma,carcinoma with nodular goiter ,and carcinoma with Hashimoto thyroiditis all greatly increase in 2008 and 2009.