摘要: |
和肽素(copeptin)是精氨酸加压素前体的羧基肽部分,它在血浆中的变化趋势和精氨酸加压素一致。且具有稳定性好,检测方便等优点,在疾病的临床诊断、预后判断方面有重要价值和优势。这一优势在心血管疾病中逐渐受到重视;和肽素对心力衰竭预后的判断一定程度上优于脑钠肽(BNP)。本文就近年来和肽素在心血管疾病临床应用中的研究进展进行综述。 |
关键词: 和肽素 冠心病 心力衰竭 |
DOI:10.11724/jdmu.2010.03.33 |
分类号:R5 |
基金项目: |
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Review of research on copeptin and angiocardiopathy |
XI Hui1, ZHOU Wen1, YU Hong-jiu2
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1.Seven-year Program of Clinical Medicine 91 K, China Medical University, Shenyang 110001, China;2.Department of VIP, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
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Abstract: |
Copeptin is the carboxyl-peptide part of precursor of arginine vasopressin. It changes consistently with arginine vasopressin. As a stable peptide and conveniently to be detected, copeptin has a lot of advantages in clinical diagnosis and prognostic judgment. Copeptin is better than BNP in prognostic judgment of heart failure. Experts of angiocardiopathy are paying more attention to these advantages. |
Key words: copeptin coronary heart disease heart failure |