腹腔镜结直肠癌手术对人体应激反应的影响

Effect of laparoscopic resection on systemic stress responses in colorectal cancer patients

关键词:  腹腔镜  结直肠癌  应激反应

Key words:  laparoscope  resection of colorectal cancer  stress response

摘要:

［目的］ 比较腹腔镜和开腹结直肠癌手术对患者机体应激反应的影响。 ［方法］ 选择同期腹腔镜和开腹结直肠癌手术患者各25例，比较两组患者术前术后C反应蛋白、IL-6、皮质醇三项应激反应指标的变化。 ［结果］ 腹腔镜组和开腹组术后血清C反应蛋白、IL-6、皮质醇水平均高于术前，但腹腔镜组水平明显低于开腹组（P<0.05）。 ［结论］ 腹腔镜结直肠癌手术对人体应激反应明显低于开腹组，创伤小，恢复快。

Abstract:

［Objective］ This study is to evaluate the systemic stress responses after laparoscopic operation for colorectal cancer patients. ［Methods］ Patients with colorectal cancer were allocated to curative laparoscopic (n=25) or conventional (n=25) operation. C-reaction protein, interleukin-6 and cortisol were examined in pre and post-operation stages to find the differences between the groups. ［Results］ Serum C-reaction protein, interleukin-6 and cortisol of post-operation stage in both groups were higher than those of pre-operation, but their post-operation levels in laparoscopic group were significantly less than those in conventional group (P<0.05). ［Conclusion］ Laparoscopic resection for colorectal cancer patients brings less systemic stress responses compared with conventional group.