大连医科大学附属第一医院围手术期抗菌药使用分析

Survey and analysis on antimicrobial administration during perioperative period

关键词:  围手术期  抗菌药物  调查

Key words:  perioperative period  antimicrobial  survey

摘要:

［目的］了解围手术期病例抗菌药应用情况，评价其用药合理性。［方法］采用回顾性调查的方法，对2006年9月~2006年12月部分外科手术、病例应用抗菌药的品种、用药频度、联合用药情况、用药时间、疗效以及药物不良反应等进行调查与分析。 ［结果］230例围手术期患者抗菌药物的应用率为100％，涉及药物32个品种，人均疗程21.89 d；各类抗菌药物使用量依次为头孢菌素类、青霉素类、喹诺酮类、氨基糖苷类和甲硝唑。联合用药合理性占43.50%。［结论］在给药途径、用药时间等方面比较合理，在预防性用药的选择及联合用药方面还有待加强管理。

Abstract:

［Objective］To understand the application of antibacterial drugs in perioperative period and evaluate the rationality of the drug prescription. ［Methods］A retrospective survey method was used to analyze the variety of antibacterial drugs, frequency of administration, combined medication, time of administration, efficacy and adverse reaction in perioperative cases from September to December in 2006. ［Results］Of the 230 cases, the utilization rate of antibacterial drugs in patients was 100 per cent, involving 32 varieties and an average 21.89 days of treatment. The dosage of cephalosporins was the highest, followed by penicillin, quinolones, aminoglycoside and metronidazole in turn. The rationality of combined medication was 43.50%.［Conclusion］It is more reasonable in route of administration and time of administration. In the choice of preventive medicine and combined medication should strengthen the management.