引用本文:袁 玲,逄丽红.紫杉类化疗方案治疗恶性肿瘤继发糖尿病的病例分析[J].大连医科大学学报,2008,30(3):263-264+278.
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紫杉类化疗方案治疗恶性肿瘤继发糖尿病的病例分析
袁 玲, 逄丽红
瓦房店市中心医院,辽宁 大连 116300
摘要:
[目的] 探讨紫杉类化疗方案对恶性肿瘤患者血糖的影响。[方法]取瓦房店中心医院2005年12月~2007年1月收治的恶性肿瘤患者124例。回顾性分析其化疗前后的血糖变化情况及相关临床资料。[结果]124例患者中,化疗后空腹血糖升高者占13.70%(17/124),其中糖耐量减低6例,占4.83%(6/124);诊断为糖尿病者6例,占4.83%(6/124);一过性血糖增高5例,占4.03% (6/124)。各患者化疗前后血糖值的差异有统计学意义(P<0.05) [结论]恶性肿瘤患者接受紫杉类化疗后可引起血糖增高,甚至发生糖耐量减低或2型糖尿病,化疗期间应密切监测血糖变化。
关键词:  恶性肿瘤  化疗  血糖  紫杉类
DOI:10.11724/jdmu.2008.03.22
分类号:R730.5
基金项目:
Research on effect of chemotherapy on blood glucose of cancer patients with taxanes agent
YUAN Ling, PANG Li-hong
Wafangdian Center Hospital,Dalian 116300,China
Abstract:
[Objective]To investigate the effect of chemoteraphy on the blood glucose of patients with Taxanes Agents.[Methods]The data of 124 patients treated in our hospital from December 2005 to January 2007 were obtained.The chang of their blood glucose and some correlated clinical data before and after chemotherapy were retrospectively analyzed.[Results]Among the 124 cases,17 cases were detected having the blood glucose increased after chemotherapy.accounting for 13.70%,including 6 cases with decreased sugar tolerance(4.83%).The difference of blood glucose of each patients between before and after chemotherapy had statistical significence(P<0.05).[Conclusions]Chemotherapy with taxanes agents could make the blood glucose of patients increased,we should monitor the glucose change of the patients.
Key words:  cancer  chemotherapy  diabetes  taxanes agents