| 摘要: |
| ［目的］通过对h-FABP、hs-CRP、cTnT 3项指标的联合检测为急性心肌梗死（AMI）的诊断提供可靠依据。［方法］cTnT检测采用金标记免疫渗滤法；hs-CRP检测采用免疫散射比浊法；h-FABP检测采用96T ELISA方法。［结果］健康组与AMI组比较，h-FABP：（5.46±0.19），（23.27±
1.77）ng/mL，P＜0.01；cTnT：（0.10±0.01），（0.64±0.11）ng/mL，P＜0.01；hs-CRP：（0.85±0.10），（17.39±4.69）mg/L，P＜0.01；cTnT、hs-CRP、h-FABP在40例AMI患者发作0~3 h阳性率分别为50%、55.26%、85%。3项指标联合分析阳性率可达98%。［结论］h-FABP、hs-CRP与cTnT联合检测对AMI早期诊断具有高灵敏性和特异性。 |
| 关键词: h-FABP；hs-CRP；cTnT；联合检测 急性心肌梗死；诊断 |
| DOI：10.11724/jdmu.2008.02.26 |
| 分类号:R446，R542.2 |
| 基金项目: |
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| Clinical Value of h-FABP，hs-CRP，cTnT examination to diagnose acute myocardial infarction |
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ZHANG Cui-ling,JIANG Yan-mei,GAO Xia,WANG Xin
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Department of Clinical Laboratory,the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
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| Abstract: |
| ［Objective］To provide the dependable data on diagnosis for AMI through checking the h-FABP, the hs-CRP and the cTnT jointly.［Methods］The cTnT was detected by the immunogold filtration assay. The hs-CRP was by the immune nephelometer measure. The h-FABP was by the 96 tests ELISA.［Results］Copared control group with AMI group, h-FABP:(5.46±0.19),(23.27±1.77)ng/mL,P＜0.01,cTnT:(0.10±0.01),(0.64±0.11)ng/mL,P＜0.01,hs-CRP:(0.85±0.10),(17.39±4.69)mg/L,P＜0.01,during 3 hours the positive rate of cTnT,hs-CRP,h-FABP was 50%, 55.26%, 85% respectively in 40 patients of AMI. The positive rate of checking jointly creased to 98%.［Conclusion］The checking jointly of the h-FABP, the hs-CRP and the cTnT is sensitive and differential for the early diagnosis for AMI. |
| Key words: h-FABP hs-CRP cTnT joint detection AMI diagnosis |
