引用本文:王洪刚,马丽红,汤新强,潘明臣.聚酰胺亲和膜包对透析液中内毒素去除的研究[J].大连医科大学学报,2008,30(1):25-28.
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聚酰胺亲和膜包对透析液中内毒素去除的研究
王洪刚1, 马丽红2, 汤新强1, 潘明臣1
1.大连医科大学 第一临床学院 临床药学教研室,辽宁 大连 116011;2.中国人民解放军210医院 临床药学教研室,辽宁 大连 116011
摘要:
[目的]研究聚酰胺亲和膜包对透析液中内毒素的去除。[方法]用鲎试剂法测定透析液中内毒素。[结果]①随着流速的增加,内毒素去除率有所下降。②温度对水溶液中内毒素的去除影响不明显。③含白蛋白透析液中内毒素的去除率较低。[结论]聚酰胺亲和膜包可有效去除透析液中内毒素,且可较高的保留各种物质的有效成分。
关键词:  聚酰胺亲和膜包  透析液  内毒素
DOI:10.11724/jdmu.2008.01.08
分类号:R94
基金项目:
Study of endotoxin removal in kidney dialysis solution by amide membrane package
WANG Hong-gang1, MA Li-hong2, TANG Xing-qiang1, PAN Ming-chen1
1.Department of Clinical Pharmacy,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;2.Department of Clinical Pharmacy, the 210 Hospital of the PLA,Dalian 116011,China
Abstract:
[Objective]To study the endotoxin removal in dialysis solution by amide membrane package.[Methods]Determination TAL (Tachypleus Amebocyte Lysate) endotoxin in dialysis solution.[Results]①With the increase of velocity, endotoxin removal rate has declined. ②Temperature on endotoxin in aqueous solution is not obvious impact of the removal. ③In albumin dialysis solution containing endotoxin removal rate is lower.[Conclusion]The amide membrane package may effectively remove the endotoxin of dialysis fluid, also may the higher retention each kind of matter effective component.
Key words:  amide membrane package  kidney dialysis solution  endotoxin