| 摘要: |
| 肿瘤浸润淋巴细胞(tumor infiltrating lymphocytes ,TIL)是指位于肿瘤细胞组织周围的淋巴细胞，具有杀伤肿瘤细胞，降低转移潜能的作用。因其与肿瘤细胞密切接触而被认为是宿主对肿瘤识别的直接而特异的表现，肿瘤组织中浸润免疫细胞数量和功能的变化在一定程度上反映了机体抗肿瘤反应的强度和总体水平。作为宿主对肿瘤免疫的最前沿倍受重视，近年来研究较多。本文对TIL及其在卵巢癌治疗中的进展作一综述。 |
| 关键词: 肿瘤浸润淋巴细胞 卵巢癌 免疫 |
| DOI：10.11724/jdmu.2007.06.29 |
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| 基金项目: |
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| Significance of TIL in ovarian cancer treatments |
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ZHAI Zhen-wei1, SHI Hong2
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1.Department of Gynaecology and Obstetrics,the Third Hospital of Liaoyang,Liaoyang 111000,China;2.Department of Gynaecology and Obstetrics,the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China
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| Abstract: |
| TIL (tumor infiltrating lymphocytes) is located around the tumor cells.TIL can destruct tumor cells and reduce their metastatic potential.As close to tumor cells,it is considered to the specific and direct performance of host identifying tumor cells.In a certain extent ,the changes of TIL's number and functions reflect the anti-tumor's strength and total level.As the forefront of host immunity,many studies have been done about it in recent years.This overview discuss TIL and it's progress in ovarian cancer treatments. |
| Key words: tumor infiltrating lymphocytes ovarian cancer immunity |
