引用本文:王卫东,高泽斌,许 方,范琳琳.肌钙蛋白T与CK-MB对急性心肌梗死诊断价值的探讨[J].大连医科大学学报,2007,29(6):587-588+593.
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肌钙蛋白T与CK-MB对急性心肌梗死诊断价值的探讨
王卫东1, 高泽斌1, 许 方1, 范琳琳2
1.大连医科大学 第二临床学院 检验科, 辽宁 大连 116027;2.大连医科大学 检验系, 辽宁 大连 116027
摘要:
[目的]探讨血清肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)对急性心肌梗死(AMI)的诊断价值。[方法]检测50例因突发胸痛、胸闷及伴有其他临床症状的急诊患者及30例同期非心血管病对照组患者血清肌钙蛋白T和肌酸激酶同工酶的浓度,并进行分析。[结果]患者组与对照组间cTnT、CK-MB值差异均有显著性意义。在检测的50例cTnT升高的患者中,心肌梗死的患者36例,占72%,同期CM-MB阳性率低于cTnT。[结论]cTnT对心肌梗死的诊断有较高的特异性与敏感性,随着发病时间延长CK-MB的敏感性、特异性逐渐升高。
关键词:  肌钙蛋白T  肌酸激酶同工酶  急性心肌梗死
DOI:10.11724/jdmu.2007.06.23
分类号:
基金项目:
cTnT and CK-MB' tests results analysis with 50 cases of AMI
WANG Wei-dong1, XU Fang1, FAN Lin-lin2
1.Department of Clinical Laboratory,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;2.Department of Clinical Laboratory of Dalian Medical University,Dalian 116027,China
Abstract:
[Objective]To study the value of serum cardiac troponin T (cTnT) and creatine kinase issonzyme MB (CK-MB) in acute myocardial infarction (AMI).[Methods]The concentrations of cTnT and CK-MB in 50 cases of sudden chest pain,emergency patients of other systems and 30 cases of non-heart and vessel diseases were detected.[Results]cTnT and CK-MB had evident difference between patients and control group.AMI patients covered 72% in 50 cases of patients whose cTnT increased.The positivity rate of CK-MB was lower than cTnT.[Conclusions]cTnT has high specificity and sensitivity in the diagnosing AMI. CK-MB's sensitivity and specificity are creasing with the length of time of disease.
Key words:  cardiac troponin T  creatine kinase issonzyme MB  acute myocardial infarction