摘要: |
[目的]探讨血清肌钙蛋白T(cTnT)和肌酸激酶同工酶(CK-MB)对急性心肌梗死(AMI)的诊断价值。[方法]检测50例因突发胸痛、胸闷及伴有其他临床症状的急诊患者及30例同期非心血管病对照组患者血清肌钙蛋白T和肌酸激酶同工酶的浓度,并进行分析。[结果]患者组与对照组间cTnT、CK-MB值差异均有显著性意义。在检测的50例cTnT升高的患者中,心肌梗死的患者36例,占72%,同期CM-MB阳性率低于cTnT。[结论]cTnT对心肌梗死的诊断有较高的特异性与敏感性,随着发病时间延长CK-MB的敏感性、特异性逐渐升高。 |
关键词: 肌钙蛋白T 肌酸激酶同工酶 急性心肌梗死 |
DOI:10.11724/jdmu.2007.06.23 |
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cTnT and CK-MB' tests results analysis with 50 cases of AMI |
WANG Wei-dong1, XU Fang1, FAN Lin-lin2
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1.Department of Clinical Laboratory,the Second Affiliated Hospital of Dalian Medical University,Dalian 116027,China;2.Department of Clinical Laboratory of Dalian Medical University,Dalian 116027,China
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Abstract: |
[Objective]To study the value of serum cardiac troponin T (cTnT) and creatine kinase issonzyme MB (CK-MB) in acute myocardial infarction (AMI).[Methods]The concentrations of cTnT and CK-MB in 50 cases of sudden chest pain,emergency patients of other systems and 30 cases of non-heart and vessel diseases were detected.[Results]cTnT and CK-MB had evident difference between patients and control group.AMI patients covered 72% in 50 cases of patients whose cTnT increased.The positivity rate of CK-MB was lower than cTnT.[Conclusions]cTnT has high specificity and sensitivity in the diagnosing AMI. CK-MB's sensitivity and specificity are creasing with the length of time of disease. |
Key words: cardiac troponin T creatine kinase issonzyme MB acute myocardial infarction |