| 摘要: |
| ［目的］ 对呼吸道感染革兰氏阴性病原菌进行了回顾性分析，探讨院内获得性铜绿假单胞菌药敏情况。［方法］ 选择2005年1月~2006年4月抚顺市中心医院住院呼吸道感染的患者，菌株来自患者清晨第一次痰。使用美国BD公司全自动细菌鉴定/药敏仪及配套软件进行细菌鉴定和药敏分析。［结果］共分离出434株阴性病原菌，其中铜绿假单胞菌为96例（22%），肺炎克雷伯氏菌162例（37%）。药敏监测本细菌对17种抗生素的敏感率依次为：美洛培南（92.7%）、亚胺培南（87.5%）、环丙沙星（82.6%）、阿米卡星（78.1%）、哌拉西林/他唑巴坦（77.7%）、左氧氟沙星（71.0%）。［结论］铜绿假单胞菌最有效的抗生素是美洛培南和亚胺培南，在治疗中，应结合本医院感染特点，合理选择抗生素，控制细菌耐药性的产生和蔓延。 |
| 关键词: 抗生素 呼吸道感染 铜绿假单胞菌 |
| DOI：10.11724/jdmu.2007.03.37 |
| 分类号:R446 |
| 基金项目: |
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| Analysis of antibiotic susceptibility of Pseudomonas aeruginosa infecting in respiratory path |
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YANG Feng-hua1, MENG Xiang-dong2, ZHOU Jing-xin1, YANG-Yue1, LI Qiu-juan3
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1.Fushun Central Hospital , Fushun 113006,China;2.The Second Company of Fushun Petroleum Hospital, Fushun 113004, China;3.Laboratory of Food Quality and safe, Dalian Medical University, Dalian 116027, China
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| Abstract: |
| ［Objective］To retrospectively study the garm-negative germ infecting in respiratory path and research antibiotic susceptibility to required Psendomonas aeruginosa in hospital.［Methods］Collect the first fresh sputum of patients whose respiratory infected in fushun central hospital from January 2005 to April 2006 .the germ identified and antibiotic susceptibility analysized by PHOENIX 100 by America BECTON DICKINSON.［Results］Separate 434 strains garm-negative germ from them Psendomonas aeruginosa 96 cases(22%) ,Klebsiella pneumoniae 162 cases(37%). Antibiotic susceptibility results to 17 kinds antibiotic are Meroperem (92.7%), Imipenem(87.5%),Ciprofloxacin (82.6%),Amikacin (78.1%), Piperacillin/Tazobactam(77.7%),Levofloxacin(71.0%).［Conclusions］Through data analyses educe the best antibiotic to Pseudomonas aeruginosa are Meroperem and Imipenem, in experientially curing ,the doctor should combine the hospital infection characteristic reasonly collect antibiotic control drug resistance arising and spreading. |
| Key words: antibiotic infection in respiratory Pseudomonas aeruginosa |
