| 摘要: |
| 短串联重复序列（STR）作为第二代遗传标记，广泛的分布于人类基因组中。本文介绍了STR及其分型特点，以及STR应用于遗传制图、法医学鉴定、人类学、群体遗传学、基因诊断、器官移植等方面内容。 |
| 关键词: STR 遗传多态性 群体遗传学 |
| DOI：10.11724/jdmu.2007.01.30 |
| 分类号:R394.5; Q346.5 |
| 基金项目: |
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| Study and advancements of human short tandem repeats |
|
MA Wei1, ZHANG Liang2, LI Yan3, XU Fei3
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1.Postgraduate 2005 Session of Dalian Medical University, Dalian 116027,China;2.Seven-Year Department 2002 Session of Dalian Medical University, Dalian 116027, China;3.Department of Anatomy, Dalian Medical University, Dalian 116027, China
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| Abstract: |
| As the second generation of genetic marks, short tandem repeats are extensively distributed in human genome. STR and its typing characteristics and applications in genetic map, forensic identification, anthropology, population genetics, gene diagnosis and organ transplantation are reviewed in this paper. |
| Key words: short tandem repeats genetic polymorphism population genetics |
