纳络酮与醒脑静合用治疗急性脑梗死42例观察

Observation to 42 cases of acute cerebral infarction treated with naloxone combined with xingnaojing

关键词:  纳络酮  醒脑静  脑梗死  神经功能缺损评分

Key words:  Naloxone, Xingnaojing, cerebral infarction, NDS

摘要:

［目的］ 观察纳络酮与醒脑静合用治疗急性脑梗死的疗效及安全性。［方法］ 86例急性脑梗死患者分为两组。治疗组42例，对照组44例。两组在常规治疗中，治疗组用纳络酮和醒脑静治疗，对照组用复方丹参与低分子右旋糖苷治疗。［结果］治疗组治疗后神经功能缺损评分（NDS）9.6±3.4，较治疗前23.6±4.6 有明显下降(p<0.01)。治疗组显效率明显优于对照组(p<0.01)。治疗组意识障碍转醒时间明显优于对照组(p<0.01)。［结论］ 纳络酮与醒脑静合用治疗急性脑梗死有肯定的疗效，可降低致残率及死亡率。

Abstract:

［Objective］ To investigate the curative effects and the safety of Naloxone combined with Xingnaojing to treat the acute cerebral infarction. ［Methods］ Of 86 patients with the acute cerebral infarction were randomly divided into two groups. In the normal treatment, the treated group of 42 cases were treated with Naloxone and Xingnaojing, while the control group of 44 cases with Co-Dansen and Low molecular weight dextran. ［Results］ Of the treated group, the neurological deficit scale scores (NDS) 9.6±3.4 treatment decreased positively23.6±4.6（p＜0.01）compared to symptoms before treatment. The effective rate in the treated group was significantly superior to that in the control group（p＜0.01）. Of the treated group, the time for consciousness recovery was clearly superior to that for the control group. ［Conclusions］ It has positive curative effects to treat the acute cerebral infarction with Naloxone combined with Xingnaojing, which can reduce the rate of causing disability and rate of death.