| 摘要: |
| [目的 ]探讨血浆纤维蛋白原水平及血小板计数与卵巢恶性肿瘤的关系。 [方法 ]选择经手术病理或临床证实的卵巢恶性肿瘤患者 4 6例 ,卵巢良性肿瘤患者 4 5例 ,所有患者治疗前抽血 ,检测血浆纤维蛋白原 (fibrinogen ,FIB)及血小板四项参数 ,包括血小板计数 (PLT)、血小板分布宽度(PDW )、平均血小板体积 (MPV)和血小板压积 (PCT) ,进行回顾性分析。[结果 ]卵巢恶性肿瘤患者平均血浆FIB含量为 (5 84 .1± 190 .4 )mg/dL(x±s) ,其平均血小板计数为 (2 6 8.0± 10 6 .4 )×10 4 /fL(x±s) ,与卵巢良性肿瘤患者比较差异显著 (P <0 .0 1)。卵巢恶性肿瘤患者的血浆FIB水平与肿瘤的病理类型和临床分期无关 ;卵巢恶性肿瘤患者的血小板计数与肿瘤的病理类型和临床分期有关。[结论 ]血小板计数及血浆纤维蛋白原水平测定 ,对筛查和早期发现卵巢恶性肿瘤有一定意义 ,可作为诊断卵巢恶性肿瘤的一种补充指标 ,并对卵巢恶性肿瘤患者病情评估与预后判断有重要意义。 |
| 关键词: 血小板计数 血浆纤维蛋白原 卵巢恶性肿瘤 |
| DOI：10.11724/jdmu.2004.04.15 |
| 分类号:R737.31 |
| 基金项目: |
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| Clinical significance of blood platelet count and serum fibrinogen in patients with ovarian carcinoma |
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1.Department of Pathophysiology, Dalian Medical University, Dalian116027,China;2.Department of Gynecology and Obstetrics, the First Affiliated Hospital,Dalian Medical University, Dalian 116011, China)
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| Abstract: |
| [Objective] To explore the clinical significance of blood platelet count and serum fibrinogen content in diagnosed ovarian carcinoma cases. [Methods] Forty-six cases of ovarian carcinoma were demonstrated by pathologic or clinical diagnosis. Serum fibrinogen (FIB) content was measured by using automated coagulation analyzer SYSMEX CA-6000, and platelet count (PLT) was measured automatically by using blood cell counter Coulter JT. [Results] The average levels of serum fibrinogen and blood platelet count in the patients with ovarian carcinoma were(584.1±190.4)mg/dL(x±s) and (268.0±106.4)×10 4/fL (x±s) respectively. Significant difference was observed in detection of PLT and serum FIB levels between ovarian carcinoma group and benign ovarian tumors group (P<0.01). [Conclusion] The level of PLT and serum FIB could be used as a complementary parameter in the diagnosis of ovarian carcinoma, and they have the important significance for the selecting and assessing the state of ovarian carcinoma. |
| Key words: blood platelet count serum fibrinogen ovarian carcinoma |
