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| 维生素D受体研究进展 |
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郗永义1, 郑秀芬2, 叶健2, 霍赛虎1, 张健1, 陈帅锋1
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1.中国人民公安大学,研究生部,北京,100038;2.公安部,物证鉴定中心,北京,100038
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| 摘要: |
| 维生素D受体(Vitamin D receptor,VDR)属于类固醇类激素,在体内主要介导维生素D的细胞作用.其基因上存在多个多态性位点,并与许多疾病发生有关.本文主要介绍了VDR的结构及功能、以及VDR基因多态性和与其相关的疾病. |
| 关键词: 维生素D 维生素D受体 骨密度 |
| DOI：10.11724/jdmu.2004.03.24 |
| 分类号:R977.2 |
| 基金项目: |
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| Vitamin D receptor and vitamin D receptor gene polymorphism research |
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XI Yong-yi1, ZHENG Xiu-fen2, YE Jian2, HUO Sai-hu1, ZHANG Jian1, CHENG Shuai-feng1
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1.Chinese People's Public Security University, Beijing 100038, China;2.. Institute of Forensic Science, Ministry of Public Security, Beijing 100038, China)
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| Abstract: |
| Vitamin D receptor(VDR) belongs to steroid hormone, it is mainly as a material of vitamin D acting on cell. There are some polymorphic loci in the VDR gene and they are associated with many diseases. The article reviews the structure and function of VDR, and its relafanship between gene polymorphisms and some diseases |
| Key words: Vitamin D Vitamin D receptor bone mineral density |