引用本文:魏巍,左云飞,李铭志,王寰,崔军阳.2型糖尿病、冠心病、脑梗塞患者血脂、载脂蛋白和脂蛋白(a)的检测及其意义[J].大连医科大学学报,2003,25(3):.
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2型糖尿病、冠心病、脑梗塞患者血脂、载脂蛋白和脂蛋白(a)的检测及其意义
魏巍1, 左云飞1, 李铭志1, 王寰2, 崔军阳3
1.大连医科大学,检验医学院,辽宁,大连,116027;2.大连石化医院,检验科,辽宁,大连,116031;3.沈阳第一人民医院,检验科,辽宁,沈阳,110015
摘要:
[目的]探讨2型糖尿病、冠心病、脑梗塞患者血浆脂质检测的临床意义.[方法]收集受试者血清,在OLIMPUS AU 1000全自动生化分析仪上进行血脂相关指标的检测分析.[结果]经过t检验统计分析认为载脂蛋白B(ApoB)、脂蛋白(a)[Lp(a)]、低密度脂蛋白(LDL-C)3项指标有显著性差异,将对2型糖尿病(NIDDM)并发冠心病(CAD)、脑梗塞(CI)起到预示作用.[结论]此3项指标对冠心病、脑梗塞的早期预测优先于其他指标.
关键词:  2型糖尿病  冠心病  脑梗塞  血脂  载脂蛋白  脂蛋白(a)
DOI:10.11724/jdmu.2003.03.21
分类号:R392
基金项目:
Detection of plasma lipid, ApoB, Lp(a) from non-insulin dependent diabetes mellitus(NIDDM) coronary heart disease(CAD)、cerebral infarction(CI) patients and analsis their significance in clinical test
WEI Wei,ZUO Yun-fei,LI Ming-zhi,WANG Huan,CUI Jun-yang
1.Department of Clianical Biochemistry, Dalian Medical University, Dalian 116027, China;2.Dalian Petrochemical Industry Hospital , Dalian 116031, China
Abstract:
To discuss the clinic significance of plasma lipid detection. [Method] detect and analyze the plasma lipid markers of the collected serums on the OLIMPUS AU 1000 automatic biochemistry analyzer .[Result]:the result of the three plasma lipid markers ,ApoB, Lp(a),LDL-C of non-insulin dependent diabetes mellitus(NIDDM) by t-test is significant. and this will predict the risk of complicated coronary heart disease(CAD),cerebral infarction(CI). [Conclusion] they are better than the others in terms of prediction of coronary heart disease(CAD),cerebral infarction(CI).The three markers should be prefer able adopted in clinical test.
Key words:  INDDM  CAD  CI  apolipoprotein  lipoprotein