高血压不同左室构型患者QT间期离散度的研究

Study of QT interval dispersion in hypertensive patients with different left ventricular geometric patterns

关键词:  高血压  左室构型  QT间期离散度

Key words:  hypertension  left ventricular geometry  QT interval dispersion

摘要:

[目的] 研究高血压不同左室构型患者QT间期离散度的变化.[方法] 应用超声心动图计算左室重量指数(LVMI)和相对室壁厚度(RWT),按LVMI和RWT将左室分为4种构型,对117例原发性高血压病人的QT间期离散度进行研究,并以45例健康人作为对照组.[结果] 高血压组除正常构型外,其余QT间期离散度均大于对照组,而向心性肥厚和离心性肥厚组大于向心性重构组,向心性重构组大于正常构型组.QT间期离散度与LVMI正相关.[结论] 高血压不同左室构型患者QT间期离散度不同,随着LVMI增加QT间期离散度加大.

Abstract:

To study the alteration of QT interval dispersion in hyper tensive patients with different left ventricular geometric patterns. ［Methods］ The left ventricular mass index (LVMI) and the relative wall thickness (RWT) were calculated using echocardiographic data, and patients' left ventricular geometry was divided into four patterns based on LVMI and RWT. The left ventricular geometry alteration and QT interval dispersion in 117 patients with essential hypertension were studied, and 45 healthy persons used as control. ［Results］ The QT interval dispersion in different left ventricular geometric groups of hypertensive patients was all larger than the normal control group except the normal geometry group. The concentric hypertrophy group and the eccentric hypertrophy group had the larger of QT interval dispersion than the concentric remodeling group, and the concentric remodeling group was larger than normal geometry group. ［Conclusions］ The QT interval dispersion is different in patients with different left ventricular geometric patterns. The larger is the cardiac structure alteration and LVMI, the more dispersed the QT interval.