| 摘要: |
| 轮状病毒是引起儿童胃肠炎最常见的病原体之一，在儿童轻度胃肠炎合并良性惊厥患儿的粪便标本中检出率较高。轮状病毒肠炎合并良性惊厥的确切发病机制尚未完全阐明，目前研究发现轮状病毒肠炎合并良性惊厥的发病机制主要与中枢神经系统感染、Na+离子通道、NSP4介导钙离子稳态失衡、一氧化氮和轮状病毒基因型有关。抗惊厥治疗推荐用于急性期的止惊，持续抗惊厥治疗不推荐使用。 |
| 关键词: 轮状病毒肠炎 胃肠炎 良性惊厥 儿童 |
| DOI：10.11724/jdmu.2018.03.18 |
| 分类号:R725.1 |
| 基金项目: |
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| Development of benign convulsion with rotavirus gastroenteritis |
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LI Rui,, TONG Jianning
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Infectious and Digestive Department, Qingdao Women and Children Hosptial, Qingdao 266000, China
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| Abstract: |
| Rotavirus is a frequent cause of gastroenteritis in children. Rotavirus has been frequently detected in the stool specimens of benign convulsion with mild gastroenteritis patients. However, these pathophysiological correlations are still unclear. It is found that the mechanisms of rotavirus gastroenteritis with benign convulsion are related to central nervous system infection, Na+channels, NSP4-induced calcium channel fluctuations, NO and rotavirus genotype. Anticonvulsant therapy is recommended in the acute phase, but continuous anticonvulsant therapy is not recommended. |
| Key words: rotavirus gastroenteritis gastroenteritis benign convulsion child |
