复发性急性胰腺炎危险因素研究进展

Research progress on the risk factors of recurrent acute pancreatitis

关键词:  复发性急性胰腺炎  危险因素  胆囊切除术  胰腺分裂

Key words:  recurrent acute pancreatitis  risk factor  cholecystectomy  pancreas division

摘要:

复发性急性胰腺炎（recurrent acute pancreatitis,RAP）是指临床上多种病因导致的急性胰腺炎（acute pancreatits,AP）反复发作（发作次数>2次）。其多次反复的发作有发展为慢性胰腺炎的倾向。明确其危险因素，并及时去除，有助于减少AP的复发。既往由于缺少明确的定义、随机临床试验、标准研究方案及长期随访性研究，更多的将未能明确病因的RAP归为特发性。现阶段随着研究的深入及检查手段的更新，更多引起胰腺炎复发的危险因素被明确。本文就现有的RAP危险因素相关研究进行综述。

Abstract:

Recurrent acute pancreatitis (RAP) is defined as acute pancreatitis (AP) caused by a variety of clinical causes (attack frequency >2). Its repeated attack has the potential of developing for chronic pancreatitis (CP). Clarifying its risk factors and appropriate treatment in time had contributed to reduce the recurrence of AP. Due to lack of clear definition, randomized clinical trials, standard research methods, and long-term follow-up studies, many AP patients without a clear cause had been classified as idiopathic. At present, with the progression of the research and the development of laboratory techniques, more risk factors causing RAP have been defined. This review particularly focuses on the present knowledge in understanding of RAP.