引用本文:李 克,王铭义,刘勇建,刘永晟,李 明,王迎新,申敬顺,韩 杰,王 峰.机械性取栓、药物溶栓及支架技术联合治疗急性颅内血管闭塞的疗效分析[J].大连医科大学学报,2017,39(4):383-386.
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机械性取栓、药物溶栓及支架技术联合治疗急性颅内血管闭塞的疗效分析
李 克1, 王铭义1, 刘勇建1, 刘永晟1, 李 明2, 王迎新2, 申敬顺2, 韩 杰2, 王 峰1
1.大连医科大学附属第一医院 介入治疗科,辽宁 大连 116011;2.大连医科大学附属第一医院 神经内科,辽宁 大连 116011
摘要:
目的 分析机械取栓、药物溶栓及支架取栓技术治疗急性颅内血管闭塞的疗效。方法 对27例急性颅内血管闭塞的患者进行腔内介入治疗。其中男性21例,女性6例。术后随访90 d,应用改良Rankin评分(mRS)进行疗效评价。结果 应用支架取栓器23例,支架结合抽吸技术3例,动脉溶栓1例。腔内治疗后即刻再通率67%,症状性脑出血11%,90 d随访预后良好率33%,死亡率18.5%。结论 特定急性缺血性脑血管病的腔内介入治疗是安全有效的方法。
关键词:  急性缺血性脑血管病  支架  机械取栓
DOI:10.11724/jdmu.2017.04.15
分类号:R459.9
基金项目:
Clinical study of endovascular treatment of acute ischemic stroke with combined mechanical thrombectomy, intra-arterial thrombolysis and stenting
LI Ke,WANG Mingyi,LIU Yongjian,LIU Yongsheng,LI Ming,WANG Yingxin,SHEN Jingshun,HAN Jie,WANG Feng
1. Department of Interventional Radiology,2. Department of Neurology, the First Affiliated Hospital of Dalian Medical University,Dalian 116011,China
Abstract:
Objective To analyze the efficacy of endovascular treatment of acute ischemic stroke with combined mechanical thrombectomy, intra-arterial thrombolysis and stenting. Methods 27 patients with acute ischemic stroke with intracranial large-vessel occlusion received endovascular treatment. Modified Rankin score was used for independence evaluation 90 days. Results Among them, 23 were treated with stent retriever, 3 with stenting combined with aspiration, 1 with intra-arterial thrombolysis. Immediate successful recanalization rate was 67%, symptomatic intracranial hemorrhage rate 11%. Good clinical outcome was achieved in 33%, and mortality after 90 days was 18.5%. Conclusion Endovascular treatment for selected patients with acute ischemic stroke is safe and effective.
Key words:  acute ischemic stroke  stent  mechanical thrombectomy