上海中心城区50岁以上人群心房颤动患病率调查及风险分析

Prevalence and risk factors of atrial fibrillation in Shanghai downtown population aged over 50

关键词:  流行病学  心房颤动  患病率  调查

Key words:  epidemiology  atrial fibrillation  prevalence  investigation

摘要:

目的　获得上海市中心城区50岁以上人群心房颤动的患病率及其相关的危险因素。方法　对社区50岁以上人群进行问卷调查及心电图检查，对其生活习惯、疾病史及房颤发病率进行统计。应用单因素和多因素Logistic回归分析房颤的危险因素。 结果　共计入选50岁以上人群3804人。男性1691人，占总人群的 44.4% 。平均年龄(70.6±8.84)岁。调查明确诊断房颤患者130例，房颤患病率为3.42%，其中男性3.55%，女性3.31%，男女差异无统计学意义（P=0.69）。随着年龄的增长，无论男女，房颤的患病率逐渐升高。Logistic多因素回归分析显示，年龄（OR=1.05，95%CI 1.02-1.07）、既往有冠心病（OR=5.44，95%CI 3.60-8.22）或瓣膜病（OR=5.90，95%CI 2.36-14.77）为房颤的危险因素，P均＜0.05。结论　上海中心城区（静安区）50岁以上人群房颤患病率较高，高龄、冠心病或瓣膜病患者更易发生房颤。

Abstract:

Objective To assess the prevalence and risk factors of atrial fibrillation in the Shanghai downtown population （Jing'an district）aged over 50. Methods Interview and ECG were conducted to each participant aged over 50 in the community, in order to analyze the habits, the history of diseases and the incidence of atrial fibrillation. Univariate and multivariate Logistic regression analysis were performed to analyze the risk factors of atrial fibrillation. Results Data were analyzed for a total of 3804 people aged 50 and above, among whom 1691 were male (44.4%) with an average age of 70.6±8.84. 130 cases of atrial fibrillation were confirmed in the study population with a prevalence of 3.42%. Among these diagnosed cases, 3.55% were males and 3.31% were females, with no significant statistical difference (P=0.69) between the genders. The prevalence of atrial fibrillation increased with age regardless of gender. Logistic multifactor regression analysis revealed that age (OR=1.05, 95%CI 1.02-1.07, P<0.05) as well as history of coronary heart disease (OR=5.44, 95%CI 3.60-8.22, P<0.05) or valvular disease (OR=5.9, 95%CI 2.36-14.77, P<0.05) were the risk factors of atrial fibrillation, P＜0.05. Conclusion The prevalence of atrial fibrillation is higher in population aged over 50 in Shanghai downtown areas. High risk factors included age, coronary heart disease and valvular disease.