高级动态血流成像技术对慢性移植肾功能不全血流灌注的显示能力研究

Advanced dynamic flow imaging in evaluation of blood flow perfusion at different stages of chronic renal dysfunction after transplant

关键词:  超声成像  高级动态血流  移植肾  慢性肾功能不全

Key words:  ultrasound imaging  advanced dramatic flow imaging  renal transplantation  chronic renal disease

摘要:

目的　比较不同彩色超声成像模式对慢性移植肾功能不全不同分期血流灌注的显示能力，明确高级动态血流成像技术(advanced dramatic flow imaging，ADF）对于慢性移植肾功能不全临床不同分期移植肾各级血管的显示能力。　方法　根据慢性肾功能不全K/DOQI诊断标准将101例慢性移植肾功能不全患者分为1～5期共5组，分别应用彩色多普勒血流成像（color doppler flow imaging，CDFI）、彩色多普勒能量图(color doppler energy imaging，CDE)和ADF检测移植肾各级血管显示情况，通过血管显示构成比及血管显示失败率的比较观察ADF对肾各级血管的显示能力。　结果　ADF对慢性移植肾功能不全1～5期血管显示构成比分别为100%，100%，94.44%，90.48%，85.71%。与CDFI和CDE相比，ADF对血管显示构成比更高，差异均有显著性意义(P<0.05)。慢性移植肾功能不全分期越高，ADF对移植肾血管显示构成比越低。与CDFI及CDE相比，ADF对慢性移植肾功能不全3～5期患者血管显示失败率更低，差异均有显著性意义（P<0.05）。慢性移植肾功能不全分期越高，移植肾血流灌注分级越低，ADF对移植肾血管显示失败率越高。　结论　与CDFI和CDE相比，ADF对慢性移植肾功能不全不同分期肾脏血管均有更强的显示能力，可为选择临床治疗方案提供重要依据。

Abstract:

Objective　 To compare the ability of different ultrasound modes in blood flow perfusion detection at different stages of chronic renal dysfunction after transplant, and to explore the superiority of advanced dynamic flow imaging (ADF) in blood flow perfusion detection at different stages of chronic renal dysfunction after transplant.　Methods　 A total of 101 patients at different stages (stage 1-stage 5) of chronic renal dysfunction after transplant were examined with color doppler flow imaging (CDFI), color doppler energy imaging (CDE) and ADF to explore the superiority of ADF in blood flow perfusion detection at different stages of chronic renal dysfunction after transplant．　Results　 The overall ratios of display for blood flow perfusion at different stages of chronic renal dysfunction after transplant by ADF were 100%，100%，94.44%，90.48% and 85.71%, higher than those by CDFI and CDE (P<0.05). Higher the stages of chronic renal dysfunction after transplant, lower were the ADF ratios of display for blood flow perfusion; while the differences among the various groups were significant (P<0.05). Compared to CDFI and CDE, ADF had lower failure ratios of display for blood flow perfusion in patients at different stages (stage 3-stage 5) of chronic renal dysfunction after transplant (P<0.05). Higher the stages of chronic renal dysfunction after transplant, lower were the ADF failure ratios of display for blood flow perfusion; while the differences among the various groups were significant (P<0.05).　Conclusion　 Compared to CDFI and CDE, ADF has a higher ratio of display for blood flow perfusion at different stages of chronic renal dysfunction after transplant, which is important for clinical treatment plan.