牙周基础治疗对患牙周炎孕妇C反应蛋白的影响

Effect of nonsurgical periodontal treatment on C-reactive protein level in pregnant women with periodontitis

关键词:  妊娠  牙周炎  C反应蛋白

Key words:  [Key words]　pregnancy  periodontitis  C-reactive protein

摘要:

[摘要]　目的　检测患牙周炎孕妇牙周基础治疗前后血清C反应蛋白(CRP)浓度的变化，为预防早产和低体重儿的发生提供科学依据。　方法　根据孕妇牙周状况分为牙周健康组和牙周炎组。牙周健康孕妇仅进行口腔卫生宣教，患牙周炎孕妇在知情同意下接受牙周基础治疗。记录初诊和每次复诊牙周探诊深度和临床附着丧失，同时检测血清CRP浓度。　结果　牙周健康孕妇牙周组织始终处于良好状态，CRP浓度亦维持在（1.17±1.03）mg/L左右；患牙周炎孕妇经过牙周基础治疗探诊深度和临床附着丧失都明显改善，CRP水平也由（4.16±1.45）mg/L降低到（1.90±1.13）mg/L，差异具有显著性意义（P<0.05）。　结论　牙周基础治疗改善患牙周炎孕妇牙周组织炎症的同时显著降低其血清CRP浓度。

Abstract:

[Abstract] Objective　To investigate serum C-reactive protein level after periodontal nonsurgical therapy in pregnant women with periodontitis and to provide scientific evidence in preventing the incidence of premature and low birth weight infants.　Methods　Pregnant women were divided into periodontal health group and periodontitis group according to the periodontal status. All patients were organized to study and learn oral health. Periodontal nonsurgical therapy was performed in periodontitis group with informed consent. Probing depth,clinical attachment loss and serum C-reactive protein level of each pregnant woman were measured in each visit.　Results　Periodontal tissue was in good status and serum C-reactive protein concentration remained about at (1.17±1.03)mg/L in periodontal healthy women throughout the study period. After periodontal nonsurgical treatment,probing depth and clinical attachment loss in pregnant women with periodontitis were significantly improved,and serum C-reactive protein concentration decreased from (4.16±1.45)mg/L to (1.90±1.13)mg/L (P<0.05).　Conclusions　Periodontal inflammation was improved and serum C-reactive protein concentration was reduced significantly in pregnant women with periodontitis by periodontal nonsurgical therapy,which would be beneficial to decrease premature birth and low birth weight infants.