| 摘要: |
| Livin作为凋亡抑制蛋白家族（IAP）中的新成员，有抑制细胞凋亡的作用，在许多肿瘤组织中高表达，与肿瘤发病机制密切相关。近年来，许多研究证明Livin与膀胱癌的发生、发展及其复发有密切相关性，本文就Livin的抗凋亡机制及其在膀胱癌诊断和治疗中的研究进展作一综述。 |
| 关键词: Livin 膀胱癌 凋亡抑制蛋白 基因治疗 |
| DOI：10.11724/jdmu.2014.01.21 |
| 分类号: |
| 基金项目:基金项目：国家自然科学基金项目（30772023） |
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| Progress in research of Livin in bladder cancer |
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LIU Xiao-qiang 1，LI Fang 21,2
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1.Seven-year Program of Clinical Medicine, Dalian Medical University, Dalian 116044, China;2. Department of Immunology, Dalian Medical University, Dalian 116044, China
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| Abstract: |
| [Abstract] Livin gene is a new member recently found in the inhibitors apoptosis (IAPs) family, which is highly expressed in many tumorous tissues and plays a great role in the pathogenesis and progression of cancer through the inhibition of cell apoptosis. In recent years, several studies have shown that Livin plays an important role in the occurrence, development and recurrence of bladder cancer. The purpose of this study was to provide a literature review of the progress in research of Livin in the diagnosis and therapy of bladder cancer. |
| Key words: [Key words] Livin urinary bladder neoplasms inhibitor of apoptosis protein gene therapy |
