18例乳腺粘液癌临床特点及预后分析

Clinical characteristics and prognosis of mucinous carcinoma of the breast (18 cases)

关键词:  乳腺肿瘤  粘液癌  临床特点  预后

Key words:  breast neoplasm  mucinous carcinoma  clinical characteristic  prognosis

摘要:

[目的] 探讨乳腺粘液癌(mucinous breast carcinoma，MBC)的临床特点及预后。[方法] 收集2004年1月—2011年10月间18例乳腺粘液癌患者的临床资料。2例行单纯乳房切除加前哨淋巴活检术（SLNB），其余16例行改良根治术。9例术后行2~6疗程的化疗，16例采用了内分泌药物治疗，2例进行了局部放疗。[结果] 术后局部麻木感5例，上肢水肿1例，皮下积液4例。病理及临床分期：单纯型粘液癌7例，混合型粘液癌11例，发生腋窝淋巴结转移4例，占22.22%；I～Ⅱ期15例，Ⅲ期3例。15例经术后随访6个月～6年，随访率83.33%，随访满5年者5例，15例生存。[结论] 乳腺粘液癌生长缓慢、转移率低，行乳腺癌改良根治术或乳房单纯切除加SLNB，术后辅以必要的化疗，患者预后较好。

Abstract:

[Objective] To explore the clinical characteristics and prognosis of MBC. [Methods] Retrospective study the clinical data of eighteen cases of MBC hospitalized in the First Affiliated Hospital of Dalian Medical University from January 2004 to October 2011, Modified radical mastectomy were performed in 16 cases，whereas simple mastectomy and SLNB were performed in 2 eases. The clinical features，treatment measures and prognosis were reviewed and analyzed．[Results] Postpoerative local numbness in 5 cases, upper extremity edema in 1case, subcutaneous fluid in 4 cases; Pathological types included 7 cases of simple type and 11 cases of mixed type． Metastasis of axillary lymph nodes occurred in 4 cases, accounting for 22.22% of the 18 eases． Stage I-II was found in 15 cases， accounting for 83.33％, stage Ⅲ in 3 cases. Fifteen cases were followed up for l6 months to 5 years with the follow-up rate of 83.33%. All patients were still living and in good health in the follow-up period．[Conclusion] For MBC，the growth is slow and the metastatic rate is low, modified radical mastectomy or simple mastectomy and SLNB were performed, and underwent chemotherapy after operation, the prognosis is better.