重度阻塞性睡眠呼吸暂停征的持续正压通气治疗分析

Analysis of treatment of continuous positive airway pressure on the severe obstructive sleep apnea hypopnea syndrome

关键词:  睡眠呼吸暂停  阻塞性  智能型经鼻正压通气治疗机

Key words:  sleep apnea  obstructive  intelligent nasal positive airway pressure machine(AUTO SET)

摘要:

［目的］探讨分析持续正压通气治疗对重度阻塞性睡眠呼吸暂停征（OSAHS）的疗效。［方法］选择经多导睡眠监测检查为重度OSAHS患者且行智能型经鼻正压通气（AUTO SET）治疗3个月的45例患者为对象。对呼吸暂停低通气指数（apneahyponeaindex，AHI）、最低/平均血氧饱和度（LSaO2/MSaO2）、平均血压等指标进行观察。［结果］治疗后患者打鼾、呼吸暂停和白天嗜睡等症状明显改善。AHI：（10.36±2.27）次/h，LSaO2：（85.91±5.37）%；MSaO2：（92.87±5.56）%，平均血压24 h SBP：（135.69±8.31）mmHg，24 h DBP：（87.42±6.65）mmHg。与治疗前AHI：（61.23±5.38）次/h，LSaO2：（42.45±5.78）%，MSaO2：（75.12±5.68）%，24 h SBP：（165.21±7.97）mmHg，24 h DBP（105.62±5.43）mmHg相比均有明显变化，差异具有显著性意义（P<0.05）。［结论］重度阻塞性睡眠呼吸暂停征经过AUTO SET治疗可缓解患者临床症状及改善睡眠指标。

Abstract:

［Objective］To investigate the effects of continuous positive airway pressure (CPAP) on severe OSAHS.［Methods］Forty-five severe OSAHS cases checked by polysomnography and treated by intelligent nasal continuous positive airway pressure (AUTO SET) for 1 year were selected for this study.All patients′ apnea hyponea index (AHI), lowest and average oxygen saturation (LSaO2/MSaO2), and blood pressure were measured.［Results］After treatment, the apnea index AHI:(10.36±2.27)/h,LSaO2:(85.91±5.37)%, MSaO2:(92.87±5.56)%, mean blood pressure 24 h SBP:(135.69±8.31)mmHg; 24 h DBP:(87.42±6.65)mmHg showed significantly change (P<0.05) if compared to pre-treatment data AHI:(61.23±5.38)/h; LSaO2:(42.45±5.78)%, MSaO2:(75.12±5.68)%, 24 h SBP:(165.21±7.97)mmHg, 24 h DBP:(105.62±5.43)mmHg.［Conclusion］Severe symptoms of obstructive sleep apnea can be improved if it is treated by AUTO SET.