溃疡性结肠炎140例临床分析

Analysis of clinical characteristics of 140 patients with ulcerative colitis

关键词:  溃疡性结肠炎  临床特征  回顾性分析

Key words:  ulcerative colitis  clinical characteristics  retrospectively analyze

摘要:

［目的］了解近年溃疡性结肠炎（Ulcerative Colitis，UC）住院患者的临床特征。［方法］回顾性分析2006年1月～2008年12月大连医科大学附属第一医院收治的140例UC患者的临床资料。［结果］UC住院例数逐年增加。其中，UC轻度者占57.1%、中度占26.3%。临床类型初发型占40.7%、慢性复发型占46.4%、暴发型仅占0.7%。主要症状有腹泻（97.1%）、腹痛（75.0%）、血便（75.0%）。有肠外表现者占15.0%。UC治疗上以氨基水杨酸类药物为主（72.1%）。单纯内科治疗总有效率达94.6%。［结论］UC近年有逐渐增加的趋势，以轻中度为主，疾病类型以慢性复发型和初发型为主，肠外表现较少，内科治疗以氨基水杨酸类药物为主。

Abstract:

［Objective］To analyze the characteristics of hospitalized patients with ulcerative colitis (UC) in the first Affiliated Hospital of Dalian Medical University in recent years.［Methods］One hundred and forty UC patients,diagnosed between Jan.2006 and Dec.2008 in the hospital were reviewed retrospectively.［Results］The hospitalized patients with UC increased yearly in the recent years.Of all hospitalized UC patients,57.1％were mild type,26.3％were moderate type.In all cases,40.7％were first onset,46.4％were chronic relapsing,and only 0.7％was acute fulminant type.The major symptoms were diarrhea (97.1％), abdominal pain (75.0％), bloody stool (75.0％).About 15.0％of UC patients had extraintestinal manifestations.The mainstay for UC treatment was still 5-aminosalicylate (5-ASA) agents.The remission rate by medicine reached 94.6％.［Conclusions］There has been an increasing number of hospitalized UC in recent years,mostly with mild to moderate severity.The major types of UC are chronic relapsing and first onset with rare extraintestinal manifestations.5-ASA is stills the mainstay agent used for the treatment of UC.