| 摘要: |
| 宫颈癌是妇产科常见的恶性肿瘤之一，在宫颈癌的发生过程中，人乳头瘤病毒（HPV）感染是重要的环境致瘤因素，但由于HPV并不能单独致瘤，细胞内遗传性因素的改变可能具有更重要的意义。端粒酶基因是近年提出的遗传易感因素之一，本文就端粒酶基因相关研究进展进行综述。 |
| 关键词: 宫颈肿瘤 染色体畸变 端粒酶基因 荧光原位杂交技术（FISH） |
| DOI：10.11724/jdmu.2010.01.28 |
| 分类号:R737.33 |
| 基金项目: |
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| Correlation between cervix lesion, telomerase and the human telomerase gene |
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HUANG Xiang-yan, SHI Hong
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Department of Obstetrics and Gynecology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China
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| Abstract: |
| Cervical cancer is a frequent neoplasm of gynecology. HPV has been known as the most important environmental tumorigenesis factor, but just itself can't produce a marked effect in tumorigenesis. The change of transmissibility in the cells may be more important. The human telomerase gene is one of the heredity risks. This review just discusses the relevant study progression. |
| Key words: uterine cervical neoplasm chromosome aberrations telomerase gene fluorescent in situ hybridization |
