| 摘要: |
| Wnt信号分子家族调控着多个组织脏器的胚胎发育。本文对目前已建立的Wnt经典传导通路的代表基因Wnt1以及Wnt非经典通路的代表基因Wnt5a等 Wnt家族基因敲除小鼠模型的胚胎发育异常进行综述。 |
| 关键词: Wnt家族 基因敲除动物 胚胎发育 |
| DOI：10.11724/jdmu.2008.06.24 |
| 分类号:R34 |
| 基金项目: |
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| Current studies of Wnt family knockout mouse models showing abnormality of embryonic development |
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LI Shan-shan1, XIAO Jing2
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1.Postgraduate 2005 Session of Dalian Medical University,Dalian 116044, China;2.Department of Oral Biology, College of Stomatology, Dalian Medical University, Dalian 116044, China
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| Abstract: |
| Wnt family of signaling molecules regulate varied of organ and tissue development. Here, we provide a comprehensive overview of the embryonic abnormality in knockout mouse models of Wnt1 and Wnt5a, which typically represent Wnt canonical and non- canonical pathway. |
| Key words: Wnt family gene knockout animal embryonic development |
