应用心肌功能指数评价风湿性二尖瓣狭窄患者左室心肌功能

Assessment of left ventricular function in rheumatic mitral stenosis patients by myocardial performance index

关键词:  风湿性二尖瓣狭窄  左心功能  定量组织速度成像  心肌功能指数

Key words:  rheumatic mitral stenosis  left ventricular function  quantitative tissue velocity imaging  myocardial performance index

摘要:

［目的］探讨心肌功能指数（MPI）评价风湿性二尖瓣狭窄患者（MS）左室心肌功能的意义。［方法］选取MS患者及正常对照者各30例，首先测量左室射血分数（LVEF），然后应用定量组织速度成像技术（QTVI），测量左室各壁二尖瓣瓣环处的时间间期并计算MPI。［结果］MS患者LVEF与正常组比较差异无显著性意义（P>0.05），MS组左室等容收缩时间（ICT）、等容舒张时间（IRT）较正常组延长，差异有显著性意义（P<0.05； P<0.01），左室射血时间（ET）较正常组缩短，左室整体MPI较正常组增大，差异有显著性意义（P<0.01；P<0.01）。直线相关分析显示MPI与二尖瓣口面积（MVA）之间存在相关性（r＝-0.35，P<0.01）。［结论］心肌功能指数（MPI）可以早期发现风湿性二尖瓣狭窄患者左室心肌整体功能的异常。

Abstract:

［Objective］To investigate the value of myocardial performance index(MPI) in rheumatic mitral stenosis (MS) patients by quantitative tissue velocity imaging(QTVI) .［Methods］Thirty MS patients and 30 healthy volunteers were enrolled. The left ventricular ejection fraction (LVEF ) was measured firstly, the cardiac intervals were measured by QTVI and MPI was calculated finally.［Results］There was no significant difference of LVEF between two groups(P>0.05) ; ICT and IRT were longer than those in the normal group (P<0.05; P<0.01, respectively) ; ET was shorter than that in the normal group(P<0.01) ; MPI in the MS group was significant higher than that in the normal group(P<0.01) . MPI correlated with mitral valve area (r＝-0.35, P<0.01) .［Conclusions］MPI by QTVI can assess early abnormalities of myocardial performance in MS patients.