CK-MB质量与活性在急性心肌梗死诊断中的价值

Value of serum CK-MB content and its activity in diagnosis of acute myocardial infarction

关键词:  CK-MB质量  CK-MB酶活性  心肌梗死

Key words:  creatine kinase isoenzyme  content determined and its enzyme activity  acute myocardial infarction

摘要:

［目的］ 比较血中肌酸激酶同功酶（CK-MB）质量与活性在急性心肌梗死（AMI）早期诊断中的价值。［方法］应用一步酶免疫法和酶法分别测定急诊AMI组、心绞痛（AP）组、健康体检组的CK-MB酶质量和活性。［结果］AMI组CK-MB质量和活性达峰值的时间相同，且AMI组CK-MB含量和活性均高于其他两组，差异有显著性意义（P<0.01）；心绞痛组CK-MB酶活性高于健康体检组，差异有显著性意义（P<0.05）。［结论］一步酶免疫法测定血中CK-MB质量是早期诊断AMI有价值、可靠的指标。

Abstract:

［Objective］To evaluate the importance of serum Creatine Kinase Isoenzyme (CK-MB) content determined and its activity in the diagnosis of acute myocardial infarction (AMI).［Methods］Serum CK-MB content and its activity were determined by a one step enzyme immunoassay and enzymologists respectively in AMI group angina group and healthy controls.［Results］CK-MB content and its activity in serum of AMI group reached peak at the same time and were significantly higher than that angina group and healthy controls, the difference was significant(P<0.01);CK-MB activity in angina group was also significantly higher than healthy controls, the difference was significant (P<0.05).［Conclusion］Serum CK-MB content determined by a one-step enzyme immunoassay is a valuable index in diagnosis of AMI.