| 摘要: |
| 比较基因组杂交(comparative genomic hybridization CGH)是一种将消减杂交和荧光原位杂交相结合的分子细胞遗传学技术,可在全部染色体区带上检测基因组间DNA拷贝数的变化并定位。本文对CGH技术及其在肿瘤研究中的进展作一综述。 |
| 关键词: 比较基因组杂交 肿瘤 分子细胞遗传学 |
| DOI：10.11724/jdmu.2006.03.34 |
| 分类号:R730 |
| 基金项目: |
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| Advances of CGH in tumor research |
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HE Qiao-jie1, TANG Ying-hua2, YANG Xing-wu2
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1.Department of Respirolog, the Second Affiliated Hospital of Dalian Medical University, Dalian 116027，China;2.Department of General surgery , the Second Affiliated Hospital of Dalian Medical University, Dalian 116027, China
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| Abstract: |
| Comparative genomic hybridization (CGH) is a molecular cytogenetics technique combined fluorescence in situ hybridization (FISH) with subtractive hybridization. It is capable of detecting and mapping relative DNA sequence copy number between genomes throughout entire genome. This article reviews the advances of CGH in the tumor research. |
| Key words: comparative genomic hybridization cancer cytogenetics |
