引用本文:刘景春,王镇山,薛 欣,顾俊明.血清降钙素原对肝硬化并发自发性细菌性腹膜炎的诊断价值[J].大连医科大学学报,2006,28(3):201-202.
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血清降钙素原对肝硬化并发自发性细菌性腹膜炎的诊断价值
刘景春1, 王镇山2, 薛 欣2, 顾俊明2
1.淄博市第四人民医院,山东 淄博 255000;2.大连医科大学 第二临床学院,辽宁 大连 116027
摘要:
[目的]探讨血清降钙素原(PCT)对肝硬化并发自发性细菌性腹膜炎的诊断价值。[方法]采用半定量固相免疫发光测量法测定17例肝硬化并发自发性细菌性腹膜炎患者血清PCT,免疫散射速率比浊法测定其血清C反应蛋白,常规方法检测外周血白细胞,同时与20例病毒性肝炎患者进行对照。[结果]血清PCT对腹膜炎诊断的敏感性(17/17)和特异性(20/20)均为100%,敏感性优于外周血白细胞计数(23.5%,4/17)(P<0.01),特异性优于C反应蛋白(5%,1/20)(P<0.01)。[结论]血清PCT测定对肝硬化并发自发性细菌性腹膜炎诊断有重要价值。
关键词:  降钙素原  细菌感染  自发性细菌性腹膜炎  肝硬化
DOI:10.11724/jdmu.2006.03.14
分类号:R575.2
基金项目:
Diagonosis value of serum procalcitonin in cirrhotic patients with spontaneous bacterial peritonitis
LIU Jing-chun1, WANG Zhen-shan2, XUE Xin2, GU Jun-ming2
1.Zibo 4th People’s Hospital,Zibo 255000,China;2.The Second Affiliated Hospital of Dalian Medical University, Dalian 116027,China
Abstract:
[Objective] To analyse initiatively the diagonosis of serum Procalcitonin (PCT) in cirrhotic patients with spontaneous bacterial peritonitis.[Methods] Serum PCT were detected by semi-quantitative solid-phase immunoassay, CRP were measured by using immunity-turbidity method and white blood cells were counted by routine method from 17 cirrhotic patients with spontaneous bacterial peritonitis and compared with 20 viral hepatitis.[Results] The sensitivity(17/17) and the specificity(20/20) of PCT were 100% for the diagnosis of patients with bacterial peritonitis .They were better than white blood cells (23.5%,4/17)(P<0.01) and CRP(5%,1/20)(P<0.01) respectively.[Conclusions] The detection of PCT has an important value in diagnosis of cirrhotic patients with spontaneous bacterial peritonitis
Key words:  procalcitonin(PCT)  bacterial infection  spontaneous bacterial