907例糖耐量异常患者的相关因素分析

Analysis of related factors in Dalian residents with impaired glucose tolerance

关键词:  IGT  年龄  肥胖  血压

Key words:  Imparied glucose tolerance  age  obesity  hypertention

摘要:

［目的］ 观察不同糖耐量状态的年龄、血压、体脂含量、腰臀比的变化，明确IGT的相关因素。［方法］ 将907例≥30岁的大连市居民分为糖耐量正常组(normal glucose tolerance, NGT)，糖耐量异常组(impaired glucose tolerance, IGT)和糖尿病组(diabetes mellitus, DM)，记录年龄、测定血压、腰臀比(waist hip rate，WHR)及体脂含量(fat percentage, FP)，进行组间比较及多因素相关分析。［结果］⑴与NGT组相比，IGT组、DM组年龄、收缩压(systolic blood pressure, SBP)、舒张压(diastolic blood pressure, DBP)、WHR及FP明显升高(p＜0.05)。⑵ 与DM组相比，IGT组年龄、SBP、DBP、WHR、FP无显著性差异(p＞0.05)。⑶将IGT组的血糖值作因变量，年龄、SBP、DBP、WHR、FP作自变量，进行多元线性回归分析，年龄(-0.08777, p<0.1)、FP(-0.1688), p＜0.1、WHR(24.14), p＜0.1 均与血糖值显著相关，而SBP(0.005541, p＞0.1)、DBP(-0.01994,p＞0.1)与血糖无相关性。［结论］ 年龄、肥胖(包括体脂含量和脂肪分布)均为IGT的相关因素，而血压不是IGT的相关因素。

Abstract:

［Objective］ To study the change of age, hypertention and obesity with various glucose level in Dalian residents. To identify related factors of IGT. ［Methods］ 907 subjects aged ≥30 years were divided into normal glucose tolerance (NGT) group, impaired glucose tolerance (IGT) group and diabetes mellitus (DM) group. Age, blood pressure, waist hip ratio and body fat contents were determined to assess the risk of IGT. ［Results］ ⑴ Compared with NGT group, age, SBP, DBP, FP and WHR are higher in IGT group and DM group (P＜0.05).⑵ Compared with DM group, age, hypertention, obesity are no notable difference between these two groups (p＞0.05).⑶ The glucose showed a significant correlation with age (-0.08777, p＜0.1), FP(-0.1688), P＜0.1 and WHR(24.14), p＜0.1, and a non-significant correlation with SBP(0.005541, p＞0.1) DBP(-0.01994), p＞0.1 by analysis of correlation with multiple linear regression method. ［Conclusion］ Age and obesity are related factors of IGT, while hypertention is not related factor.