| 摘要: |
| P物质（substance P, SP）作为中枢神经系统（central nervous system, CNS）的一种肽类神经递质或神经调质，在神经系统中有重要的生理和病理作用。在帕金森病（Parkinson's disease, PD）中，SP代谢发生变化，且被认为在该病的发病过程中起到某些作用?疚木蚐P及其与PD发病的关系作一综述。 |
| 关键词: 帕金森病 P物质 神经递质 |
| DOI：10.11724/jdmu.2005.02.35 |
| 分类号:R322.81 |
| 基金项目: |
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| Substance P and Parkinson's disease |
|
MA Xiao-kai, FAN Kai
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Department of Anatomy, Dalian Medical University, Dalian 116027, China
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| Abstract: |
| Substance P(SP) as neuromodulator or neurotransmitter played an important physiological and pathological role in central nervous system. The metabolic level of SP changed in Parkinson's disease(PD), and correlated with the occurrence and development of the disease. The article summarized the progress of researches about correlationship between SP and pathogenesis of PD. |
| Key words: Parkinson's disease substance P neurotransmitter |
